What we will study from sequencing 1 million human genomes with huge knowledge

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The first draft of the human genome was published 20 years ago in 2001, took practically three years and price between US$500 million and $1 billion. The Human Genome Project has allowed scientists to learn, virtually finish to finish, the three billion pairs of DNA bases – or “letters” – that biologically outline a human being.

That mission has allowed a brand new era of researchers like me, presently a postdoctoral fellow on the National Cancer Institute, to determine novel targets for cancer treatments, engineer mice with human immune systems and even construct a webpage where anyone can navigate the entire human genome with the identical ease with which you employ Google Maps.

The first full genome was generated from a handful of nameless donors to attempt to produce a reference genome that represented greater than only one single particular person. But this fell far in need of encompassing the wide diversity of human populations in the world. No two persons are the identical and no two genomes are the identical, both. If researchers needed to grasp humanity in all its variety, it will take sequencing hundreds or tens of millions of full genomes. Now, a mission like that’s underway.

Credit: Gerd Altmann from Pixabay

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